HEALTHY LIVING · SUBJECT 4

Substance Use
& Prevention

Explore tobacco, nicotine, vaping, alcohol and other psychoactive substances—and discover how choices, relationships, environments, commercial forces and public policies shape health.

SELF → FAMILY & PEERS → COMMUNITY → COUNTRY → WORLD
GHE PRINCIPLE Healthy choices. Healthier conditions.

WHY THIS MATTERS

Health choices happen in real-world environments.

Substance use is not simply a question of individual willpower. What people experience is influenced by biology, age, relationships, stress, social norms, advertising, availability, prices, laws, culture and opportunities for support.

Global Health Explorers looks at the whole picture. We learn how to make informed decisions while also asking a bigger question: What can communities and societies do to create healthier conditions?

PERSONAL HINTS

Start with what you can control.

You do not have to solve the whole problem at once. Small decisions, supportive relationships and good information can strengthen your ability to protect your health.

01

Pause before a decision

Give yourself time to think rather than allowing pressure, advertising or a stressful moment to make the decision for you.

02

Know your influences

Notice how friends, media, algorithms, products, prices and social expectations can influence what seems normal.

03

Protect your future self

Learning about risks early can help you make decisions that support your health, learning, relationships and future goals.

04

Ask for help early

Reaching out to a trusted adult or qualified professional is a strength—not a failure.

GLOBAL HEALTH AT A GLANCE

Substance use affects people and societies worldwide.

7M+ deaths each year are attributed to tobacco use.
2.6M deaths were attributed to alcohol in 2019.
200+ diseases, injuries and health conditions have causal links with alcohol.
1.2B people worldwide use tobacco, according to WHO.

These numbers describe population-level impacts. They do not define any individual person, and they do not tell the whole story about why substance use occurs.

EXPLORE

What is a psychoactive substance?

Psychoactive substances are substances that can affect the brain and influence mood, perception, thinking or behaviour.

Tobacco & nicotine

Tobacco products contain nicotine, a highly addictive substance. Tobacco smoke also contains many harmful chemicals.

Alcohol

Alcohol contains ethanol, a psychoactive and toxic substance that can contribute to many health and social harms.

Other psychoactive substances

Different substances can affect the brain and body in different ways. Their risks depend on the substance, the person, the context and patterns of use.

Context matters

Public health therefore examines more than the substance itself. It also considers age, environment, social conditions, policies, access to support and commercial influences.

GHE Safety Note

This page is for health education and prevention. It does not provide instructions for obtaining, using or experimenting with substances.

LEARN · 01

Tobacco & smoking

Tobacco harms nearly every organ of the body and is a major preventable cause of disease and premature death.

Health effects

Tobacco use is associated with cancer, cardiovascular disease, stroke, lung disease and other serious health problems.

Second-hand smoke

People who do not smoke can still be harmed by exposure to tobacco smoke.

Addiction

Nicotine can produce dependence, making stopping difficult for some people. Prevention and accessible support both matter.

Evidence: WHO identifies tobacco as a major cause of preventable death and disease and states that all forms of tobacco are harmful.

LEARN · 02

Nicotine & vaping

New technologies can change how nicotine is delivered, but changing the delivery system does not make nicotine harmless.

Why adolescence matters

The brain continues developing during adolescence and young adulthood. WHO notes that nicotine exposure during this period can affect brain development, including attention and learning, and early use can increase the likelihood of longer-term dependence.

Prevention therefore means protecting young people from unnecessary exposure while ensuring that those who need support can receive it.

LEARN · 03

Alcohol

Alcohol is a psychoactive and toxic substance associated with a wide range of health and social consequences.

More than one pathway

Alcohol contributes to injuries, noncommunicable diseases, some infectious diseases and mental health and behavioural conditions.

Risk is contextual

Risk varies with factors including amount, frequency, age, health status and circumstances.

Prevention matters

Healthy environments, good information, supportive relationships and effective policies can reduce alcohol-related harm.

LEARN · 04

Other psychoactive substances

Different substances have different effects and risks. Public health education focuses on accurate information, prevention, harm reduction where appropriate, treatment and respect.

Avoid the “good substance / bad substance” shortcut.

A Global Health Explorer asks better questions: What are the health effects? Who is most vulnerable? What social conditions shape exposure? What policies protect people? What evidence supports prevention and treatment?

LEARN · 05

Why adolescence matters

01

Brain development

Adolescence is a period of important biological, social and cognitive development.

02

Identity & belonging

Young people are developing identities, relationships and a sense of belonging.

03

Experimentation & pressure

Social environments can influence what feels acceptable or expected.

04

Prevention opportunity

Early, accurate education can strengthen health literacy and protective environments.

HEALTHY CHOICES

What does a healthy choice look like?

Healthy choices are not about perfection. They are about having information, support, opportunities and environments that make healthier decisions possible.

01

Protect your health

Learn about risks and avoid unnecessary exposure to harmful substances.

02

Protect your relationships

Build relationships where people can say no, ask questions and support one another.

03

Protect your future

Think about how decisions today can influence learning, health and future opportunities.

04

Protect your environment

Support homes, schools, communities and policies that make healthy choices easier.

Healthy choice ≠ individual blame. Public health asks how we can improve both choices and the conditions surrounding those choices.

THINK

Peers, belonging & social norms

People are social. What we believe others are doing can influence our own perceptions and decisions.

ASK

What seems “normal”?

Is your perception based on direct experience, social media, advertising or assumptions?

ASK

Who benefits?

When a product becomes popular, who gains financially from that popularity?

ASK

Who is missing?

Which young people may have fewer opportunities for support or healthier environments?

CONNECT

Stress, mental health & supportive environments

Stress and difficult life circumstances can affect health behaviours. Prevention therefore includes strengthening supportive environments—not blaming individuals for experiencing difficulties.

Supportive relationships

Trusted friends, family members, teachers and other supportive adults can provide connection and help-seeking pathways.

Healthy coping

Sleep, physical activity, meaningful activities, connection and constructive problem-solving can support wellbeing.

Professional support

When concerns become difficult to manage, qualified health professionals can provide appropriate assessment and support.

Respect

People experiencing substance-related problems deserve dignity, evidence-based care and freedom from stigma.

THINK · SYSTEMS

Commercial determinants of health

Health is influenced by how products are designed, promoted, priced, distributed and regulated.

01

Product design

Product characteristics can influence attractiveness, use and patterns of consumption.

02

Marketing

Advertising and promotional strategies can shape perceptions, preferences and social norms.

03

Price & availability

Economic and physical availability can influence population exposure.

04

Policy influence

Regulation, lobbying and political processes can shape the environments in which health decisions occur.

Global Health Explorer question: If a product is profitable, does that automatically mean it is good for health?

THINK · DIGITAL ENVIRONMENTS

Marketing, media & algorithms

Digital environments can make marketing more personal, persistent and difficult to recognize.

Sponsored content

Promotional messages can sometimes resemble ordinary entertainment or social content.

Personalisation

Digital advertising can use information about online behaviour to target audiences.

Influencers

Popular personalities can influence perceptions of what is attractive, acceptable or normal.

Media literacy

Ask: Who created this? Who paid for it? What do they want me to think, feel or do?

CONNECT · SOCIAL DETERMINANTS OF HEALTH

Look beyond the individual.

Substance-related health outcomes can be shaped by the conditions in which people grow, learn, work and live.

Family & relationships

Support, communication and connection can influence resilience and wellbeing.

Education

Health literacy and safe learning environments can strengthen prevention.

Income & opportunity

Economic conditions influence exposure, stress and access to support.

Housing & neighbourhood

Living conditions can affect safety, stress and access to healthy opportunities.

Culture & belonging

Identity, community connection and social inclusion can shape health and wellbeing.

Policies & systems

Laws, regulation, health services and public policy shape the wider environment.

SDH question: Would every young person have the same choices if their living conditions were different?

PREVENTION

Prevention is not blame.

Effective prevention combines individual skills, supportive relationships, healthy environments, evidence-based services and public policy.

01

Build knowledge

Give young people accurate, understandable health information.

02

Strengthen protective factors

Support belonging, education, positive relationships and meaningful opportunities.

03

Improve environments

Make schools, communities and public spaces safer and more supportive.

04

Provide help

Ensure people can access appropriate, respectful and evidence-based support.

05

Use policy

Regulation can reduce exposure to harmful products and commercial influence.

06

Reduce stigma

Respectful language and compassionate care can make it easier for people to seek help.

GLOBAL POLICY

WHO MPOWER

Tobacco control shows how population health can combine evidence, policy and implementation.

M

Monitor

Monitor tobacco use and prevention policies.

P

Protect

Protect people from tobacco smoke.

O

Offer help

Offer support for quitting tobacco use.

W

Warn

Warn people about tobacco's dangers.

E

Enforce

Enforce restrictions on tobacco advertising.

R

Raise

Raise tobacco taxes to reduce consumption.

CONNECT

From SELF to WORLD

Global health thinking moves outward. Start with your own decisions, then examine the systems and environments around you.

1

SELF

What information and habits can protect my health?

→
2

FAMILY & PEERS

How do relationships and social norms influence us?

→
3

COMMUNITY

What can schools and communities do differently?

→
4

COUNTRY

What laws and health policies protect people?

→
5

WORLD

How can countries cooperate to improve health?

THINK LIKE A GLOBAL HEALTH EXPLORER

Ask better questions.

A Global Health Explorer does not stop at “Is this good or bad?” We investigate causes, evidence, equity and possible solutions.

01

What is the evidence?

Separate strong evidence from claims, opinions and advertising.

02

Who is affected?

Look at age, geography, income and other dimensions of health equity.

03

Why does it happen?

Investigate biological, social, commercial and policy causes.

04

What could change?

Move from describing a problem to identifying realistic actions.

SUSTAINABLE DEVELOPMENT GOALS

Substance use is connected to wider global goals.

SDG 3

Good Health & Well-Being

Prevent disease, reduce avoidable harm and strengthen access to health and support.

SDG 4

Quality Education

Health literacy and education can help young people make informed decisions.

SDG 10

Reduced Inequalities

Prevention should address unequal exposure, unequal opportunities and unequal access to support.

SDG 16

Peace, Justice & Strong Institutions

Effective regulation, accountability and trustworthy institutions are important for health protection.

SDG 17

Partnerships for the Goals

Global health challenges require cooperation among governments, communities, researchers and civil society.

GLOBAL HEALTH & EVIDENCE

Evidence helps us move from opinion to action.

Global Health Explorers uses authoritative sources and encourages young people to ask where evidence comes from and how reliable it is.

WHO Commercial Determinants

Learn how commercial activities and strategies can influence population health.

Explore the evidence →

ONE STEP YOU CAN TAKE

Learn to recognize influence.

The next time you see a health-related claim, product promotion or social-media message, pause and ask: Who created this message, who benefits from it, and what evidence supports it?

REFLECT → ACT

Turn learning into responsible action.

REFLECT

What surprised you?

Identify one idea that changed or challenged your understanding.

INVESTIGATE

Check one claim.

Find an authoritative source and compare its evidence with what you have seen online.

CONNECT

Discuss respectfully.

Share what you learned with a trusted person without judging people who may need help.

ACT

Improve one condition.

Suggest one realistic way your school, family or community could strengthen prevention or health literacy.

CHECK YOUR LEARNING

12 Global Health Explorer MCQs

Choose the best answer. Open the explanation only after you have made your choice.

01 Which statement best describes a psychoactive substance?

A. A substance that only affects digestion

B. A substance that can affect the brain and influence mood, perception, thinking or behaviour

C. Any food containing sugar

D. Only prescription medicines

Correct answer: B

Psychoactive substances can affect the central nervous system and influence mental or behavioural processes.

02 Why is nicotine exposure particularly important during adolescence?

A. Adolescents cannot experience addiction

B. Nicotine has no effects on the brain

C. The developing brain can be affected by nicotine exposure

D. Nicotine only affects the lungs

Correct answer: C

WHO notes that nicotine exposure during adolescence can affect brain development, including attention and learning.

03 Which statement about tobacco is most accurate?

A. All tobacco products are harmless if used occasionally

B. Only cigarettes can cause health problems

C. Tobacco can harm many organs and increase disease risk

D. Second-hand smoke has no health relevance

Correct answer: C

Tobacco use is associated with multiple diseases affecting many organs, and second-hand smoke can also harm people who do not smoke.

04 Which is an example of a commercial determinant of health?

A. Product marketing and pricing

B. A person's eye colour

C. The weather on one particular day

D. A school timetable alone

Correct answer: A

Commercial determinants include activities such as marketing, pricing, product design, availability and political influence.

05 What is the best response to a persuasive health-related advertisement?

A. Believe it automatically

B. Ignore all evidence

C. Ask who created it, who benefits and what evidence supports it

D. Share it immediately

Correct answer: C

Media literacy involves examining the source, purpose, incentives and evidence behind a message.

06 Which statement best describes prevention?

A. Blaming individuals for every health outcome

B. Combining knowledge, supportive environments, services and policy

C. Avoiding all discussion of health risks

D. Using only one intervention everywhere

Correct answer: B

Effective prevention works at multiple levels: individual, interpersonal, community, health-system and policy levels.

07 Which question best reflects a Social Determinants of Health perspective?

A. Why did one person simply make a bad choice?

B. What conditions shape the choices available to different people?

C. Which person should be blamed?

D. Why does policy never matter?

Correct answer: B

An SDH lens examines how living conditions, education, income, relationships, environments and systems shape health.

08 Which WHO MPOWER action focuses on helping people stop using tobacco?

A. Monitor

B. Offer help to quit

C. Warn

D. Raise taxes

Correct answer: B

MPOWER includes offering help to quit alongside monitoring, protecting people, warning, enforcing advertising restrictions and raising taxes.

09 Which SDG is most directly connected to substance-use prevention and health?

A. SDG 3

B. SDG 7

C. SDG 14

D. SDG 15

Correct answer: A

SDG 3 focuses on Good Health and Well-Being and includes important substance-related health targets.

10 Why should prevention avoid stigma?

A. Stigma makes health information more accurate

B. Stigma can make people less willing to seek support

C. Stigma improves health services

D. Stigma is required for prevention

Correct answer: B

Respectful, non-judgmental approaches can make it easier for people to discuss concerns and seek appropriate support.

11 Which sequence best represents the GHE spatial pathway?

A. WORLD → SELF → COUNTRY → COMMUNITY

B. SELF → FAMILY & PEERS → COMMUNITY → COUNTRY → WORLD

C. COUNTRY → SELF → WORLD → FAMILY

D. COMMUNITY → WORLD → SELF → COUNTRY

Correct answer: B

GHE moves from the individual outward, connecting personal health with relationships, communities, countries and the world.

12 Which question best demonstrates global-health thinking?

A. Who is to blame?

B. How can we make the problem disappear from discussion?

C. What evidence exists, who is affected, what causes inequality, and what could change?

D. Which single solution works everywhere?

Correct answer: C

Global health combines evidence, systems thinking, equity, context and action rather than relying on blame or one-size-fits-all solutions.

GLOBAL HEALTH LEADERSHIP

Prevention needs leaders who understand both people and systems.

A future global health leader combines scientific evidence with empathy, equity, communication and responsible action.

Evidence

Ask what is known and how confidently we know it.

Equity

Ask who benefits, who is exposed and who may be left behind.

Empathy

Understand people without reducing them to labels or statistics.

Action

Turn knowledge into realistic, responsible improvements.

EVIDENCE & REVIEW

Built from public-health evidence.

This learning page draws primarily on authoritative evidence and guidance from the World Health Organization and related public-health sources.

Evidence review September 2026
Next review September 2027